A complete collection of Michelle Howard’s publications can be found at Google Scholar or ResearchGate.
Combination Therapy with Pharmacological Ascorbate and Rucosopasem Selectively Radiosensitizes Colorectal Tumors to Clinically Relevant Radiation Doses
George BN, Pulliam CF, Petronek MS, King, S. A., Awasthi, K., Fath, M. A., O’Leary, B. R., Loeffler, B. T., Spitz, D. R., Howard, ME, Beardsley, R. A., & Caster, J. M. Combination Therapy with Pharmacological Ascorbate and Rucosopasem Selectively Radiosensitizes Colorectal Tumors to Clinically Relevant Radiation Doses. Radiation Research. 2026 Sep;206(4):355–366.
Abstract: Differential Redox Capacity In Pediatric and Adult High-Grade Gliomas Reveals Therapeutic Vulnerabilities
B.E. Buzdugan, S.A. King, K.M. Spitler, B.R. O’Leary, Z. Wang, B.A. Wagner, R. Rheem, A.L. Simons, D.R. Spitz, M.E. Howard. Differential Redox Capacity In Pediatric and Adult High-Grade Gliomas Reveals Therapeutic Vulnerabilities, International Journal of Radiation Oncology*Biology*Physics, Volume 126, Issue 1, Supplement, 2026, Pages e11-e12, ISSN 0360-3016, https://doi.org/10.1016/j.ijrobp.2026.06.680.
Radioprotection of healthy tissue via nanoparticle-delivered mRNA encoding for a damage-suppressor protein found in tardigrades
Kirtane AR, Bi J, Rajesh NU, Tang C, Jimenez M, Witt E, McGovern MK, Cafi AB, Hatfield SJ, Rosenstock L, Becker SL, Machado N, Venkatachalam V, Freitas D, Huang X, Chan A, Lopes A, Kim H, Kim N, Collins JE, Howard ME, Manchkanti S, Hong TS, Byrne JD, Traverso G. Radioprotection of healthy tissue via nanoparticle-delivered mRNA encoding for a damage-suppressor protein found in tardigrades. Nat Biomed Eng. 2025 Aug;9(8):1240-1253. doi: 10.1038/s41551-025-01360-5. Epub 2025 Feb 26. PMID: 40011582; PMCID: PMC12919043.
Additive Effects of Cu-ATSM and Radiation on Survival of Diffuse Intrinsic Pontine Glioma Cells
King SA, Solst SR, Graham CH, Fiore LZ, Rheem R, Tomanek-Chalkley A, Fath MA, Caster JM, Spitz DR, Howard ME. Additive Effects of Cu-ATSM and Radiation on Survival of Diffuse Intrinsic Pontine Glioma Cells. Radiat Res. 2024 Nov 4. doi: 10.1667/RADE-24-00076.1. PMID: 39492578.
Rapid Peroxide Removal Limits the Radiosensitization of Diffuse Intrinsic Pontine Glioma (DIPG) Cells by Pharmacologic Ascorbate
Solst SR, Mapuskar KA, Graham CH, King SA, Rheem R, Current K, Allen BG, Caster JM, Spitz DR, Howard ME. Rapid Peroxide Removal Limits the Radiosensitization of Diffuse Intrinsic Pontine Glioma (DIPG) Cells by Pharmacologic Ascorbate. Radiat Res. 2023 Nov 1;200(5):456-461. doi: 10.1667/RADE-23-00006.1. PMID: 37758035; PMCID: PMC10759934.