Breadcrumb
Publications
A complete collection of Michelle Howard’s publications can be found at Google Scholar or ResearchGate.
Pre-Print: Inhibiting sirtuin-dependent DNA repair and oxidative stress responses impairs DIPG cell survival
King SA, Rheem R, Spitler KM, O'Leary BR, Graham CH, Solst SR, Teesch LM, Sho S, Byrne JD, Spitz DR, Howard ME. Inhibiting sirtuin-dependent DNA repair and oxidative stress responses impairs DIPG cell survival. Res Sq [Preprint]. 2025 Nov 21:rs.3.rs-7723497. doi: 10.21203/rs.3.rs-7723497/v1. PMID: 41333420; PMCID: PMC12668155.
Radioprotection of healthy tissue via nanoparticle-delivered mRNA encoding for a damage-suppressor protein found in tardigrades
Kirtane AR, Bi J, Rajesh NU, Tang C, Jimenez M, Witt E, McGovern MK, Cafi AB, Hatfield SJ, Rosenstock L, Becker SL, Machado N, Venkatachalam V, Freitas D, Huang X, Chan A, Lopes A, Kim H, Kim N, Collins JE, Howard ME, Manchkanti S, Hong TS, Byrne JD, Traverso G. Radioprotection of healthy tissue via nanoparticle-delivered mRNA encoding for a damage-suppressor protein found in tardigrades. Nat Biomed Eng. 2025 Aug;9(8):1240-1253. doi: 10.1038/s41551-025-01360-5. Epub 2025 Feb 26. PMID: 40011582; PMCID: PMC12919043.
Additive Effects of Cu-ATSM and Radiation on Survival of Diffuse Intrinsic Pontine Glioma Cells
King SA, Solst SR, Graham CH, Fiore LZ, Rheem R, Tomanek-Chalkley A, Fath MA, Caster JM, Spitz DR, Howard ME. Additive Effects of Cu-ATSM and Radiation on Survival of Diffuse Intrinsic Pontine Glioma Cells. Radiat Res. 2024 Nov 4. doi: 10.1667/RADE-24-00076.1. PMID: 39492578.
Rapid Peroxide Removal Limits the Radiosensitization of Diffuse Intrinsic Pontine Glioma (DIPG) Cells by Pharmacologic Ascorbate
Solst SR, Mapuskar KA, Graham CH, King SA, Rheem R, Current K, Allen BG, Caster JM, Spitz DR, Howard ME. Rapid Peroxide Removal Limits the Radiosensitization of Diffuse Intrinsic Pontine Glioma (DIPG) Cells by Pharmacologic Ascorbate. Radiat Res. 2023 Nov 1;200(5):456-461. doi: 10.1667/RADE-23-00006.1. PMID: 37758035; PMCID: PMC10759934.