Additive Effects of Cu-ATSM and Radiation on Survival of DIPG

New publication out! 🧪✨ Our latest study explores how combining Cu-ATSM with radiation therapy boosts survival effects in DIPG cells, paving the way for innovative approaches against this tough-to-treat pediatric cancer.

Pumpkin Decorating Contest

The Howard Lab submitted two pumpkin decorating entries into the First Annual Radiation Oncology Pumpkin Decorating contest. Patients vote for their favorite and winners receive a celebratory lunch. 

Being a pediatric focused research lab full of Harry Potter fans - our pumpkins represent our lab well! 

Pumpkin Contest

2024 Summer Undergraduate Presentations

With the end of July came the end of our summer undergraduate research programs. The Howard Lab summer undergraduate interns had the chance to showcase their work in multiple poster and oral presentations. Great work Eryka, Aaron, and Alyson!!

Research Laboratory Excellence in Safety Award

The Howard lab was awarded an Excellence in Safety award for their unwavering commitment to safety, collaboration, and proactive measures. 

safety award

2024 HCCC Scientific Retreat

The annual HCCC Scientific Retreat was hosted at the Hyatt Regency Conference Center in Coralville, Iowa. At this event, students, postdocs, fellows, residents, faculty, and clinicians gathered to hear and discuss the latest updates in cancer research at Holden.  

 

At this event, Dr. Shane Solst gave an oral presentation titled “Sirtinol inhibition of sirtuins decreases DNA repair in diffuse intrinsic pontine gliomas.” Congratulations to Shane for being one of eight scientists chosen to present at this event! 

 

In addition, Rana did a great job presenting Howard Lab data at the interactive poster session. 

Katie Spitler joins the lab!

We are pleased to introduce our newest addition to the Howard Lab, Katie Spitler! Dr. Spitler is a research associate with 10 years of experience doing research at the University of Iowa. She obtained her PhD in Physiology from Augusta University, and we are thrilled to welcome such a skilled and passionate team member. 

Katie

Welcoming Eryka, Alyson, and Aaron - Summer Undergraduates - to the Howard Lab!

Undergraduates interested in medical and/or scientific careers benefit from summer research experiences where they have the opportunity to fully immerse themselves in full time research for 10 weeks in the summer. Programs represented in this cohort are:  

 

Cancer Research Opportunities at Iowa (CROI) - funded by the American Cancer Society 

 

Summer Cancer Undergraduate Research Program (SCURP) for underrepresented minority students - funded by the Midwest FLASH Program 

2024 Translational Science

The 2024 Translational Science Annual Meeting was hosted in Las Vegas, NV from April 3-5. This conference welcomes trainees, junior faculty, and senior scientists for a week of networking and sharing science. All Iowa K12 CTSA scholars (including Dr. Howard) from the University of Iowa were in attendance.

Dr. Howard and her family did some hiking in Zion National Park before returning to the lab.

Bri O'Leary joins the lab!

Dr. Bri O'Leary is a research specialist who has over 10 years experience in cancer research at the University of Iowa. She has her Ph.D. in Biochemistry from the University of South Florida and a mountain of publications.   

Bri O'Leary

Bri O'Leary Ph.D.

2023 CABTRAC

The 2023 Cancer Biology Training Consortium (CABTRAC)  Annual Retreat was hosted in Orange County, California from October 22-24. This retreat invites all CABTRAC members from various cancer training and education teams across the country to gather for networking, science, and social events.

Dr. Shane Solst presented his research during an interactive poster session. 

Dr. Solst presenting at CABTRAC
Shane Presenting

First Howard Lab Publication

New research by the Howard Lab reveals that high-dose ascorbate (P- AscH-) doesn't enhance the radiosensitivity of Diffuse Intrinsic Pontine Glioma (DIPG) cells, unlike adult glioma models. DIPG have a strong ability to rapidly remove hydroperoxides, preventing ascorbate from improving their radiation response. This study highlights the critical need for strategies to improve outcomes for DIPG patients.

2023 International Congress for Radiation Research

On August 27-30th, the 17th annual International Congress for Radiation Research (ICRR) was held in Montréal, Canada. This year, the conference was combined with the 69th Annual Meeting of the Radiation Research Society (RRS). This international Congress enabled scientists in the diverse radiation science disciplines to discuss and showcase their findings, while promoting the interdisciplinary nature of radiation research. Dr. Shane Solst of the Howard Lab presented his research during an interactive poster session.

Dr. Shane Solst next to his poster at ICRR
Dr. Andrean Simons-Burnett (middle) Dr. Prabhat Goswami (left), and Dr. Shane Solst (right) representing the University of Iowa Free Radical and Radiation Biology Program at ICRR

Koffi joins the lab!

Koffi , the newest member of the Howard Lab, is an ICARE Fellow here at UIowa. The ICARE (Iowa Cancer Research Experience) Program, hosted by Holden Comprehensive Cancer Center, is a post-baccalaureate program that encourages institutions to diversify their student and faculty populations. 

Welcome to the lab, Koffi!

kofs

American Association of Physicists in Medicine

Dr. Michelle Howard gave a podium talk at the AAPM meeting in Houston, Texas. 

Michelle at Conference 2023

Summer Undergraduate Research Conference

Sarah and Claire presented their work at the summer undergraduate research conference to end their time as BSURP and SUMR students!

sarah poster
claire poster